Coffee Intake Linked to Longer Prostate Cancer-Specific Survival

THURSDAY, Sept. 22, 2022 (HealthDay News) -- High coffee intake is associated with longer prostate cancer-specific survival (PCSS) for certain subgroups of men, including those with the CYP1A2 AA genotype, according to a study published online Aug. 19 in European Urology Oncology.

Justin R. Gregg, M.D., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues examined the associations between coffee intake, caffeine metabolism genotype, and survival using data from the PRACTICAL Consortium database for 5,727 men with prostate cancer. Cases had data available for the CYP1A2 163C>A rs762551 single-nucleotide variant associated with caffeine metabolism, coffee consumption, and follow-up of more than six months.

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